Prednisolone what is it? What are the effects?

 Any Luppie or anyone dealing with a chronic condition is likely to have a love hate relationship with Prednisolone.

I thought it would be a good idea to do a little research into this drug that I have been taking on and off for over a decade and write this blog post in the hopes that it could help anyone that has been newly diagnosed or even the friends and family of a person with a chronic condition in order for them to provide support


Photo by Klaus Nielsen from Pexels

What is Prednisolone?

Prednisolone is a synthetic form of a natural substance (corticosteroid hormone) produced by the adrenal glands and used to treat arthritis, blood problems, immune system diseases, skin and eye diseases, respiratory diseases, cancer, and allergies. It reduces the immune system's response to various diseases to relieve symptoms such as pain, swelling, and allergic reactions.

How to use oral Prednisolone?

       Take this medication by mouth, food, or milk exactly as directed by your doctor to avoid indigestion. Dosing with a special measuring device/spoon.

       Do not use homemade spoons because you will not get the correct dosage.

       Liquid prednisone has many brands, advantages, and forms. Please read the dosage instructions for each product carefully, as the dosage of prednisolone varies from product to product. See also the precautions and storage section. Follow the dosage plan carefully.

       The dose and duration of treatment will depend on your health and response to treatment.

Photo by uncoveredlens from Pexels

Side Effects

You may experience





       Menstrual cycle changes

       Sleep disturbance

       Increased sweating


 If these effects persist or worsen, please tell your doctor or pharmacist as soon as possible. Remember, your doctor prescribed this medicine because they found it to be good for you.

Infections: Many people who take this drug do not experience serious side effects. Because this drug weakens the immune system, it reduces your ability to fight infections. This increases your chances of getting serious (rarely fatal) infections or developing a certain type of infection. If you have any signs of infection (such as cough, sore throat, fever, chills), please tell your doctor immediately.

Yeast Infections: Long-term or repeated use of this drug can cause thrush or yeast infections. If you notice white spots in your mouth or changes in vaginal discharge, consult a doctor.

Blood Sugar Level: In rare cases, this drug can increase blood sugar levels, which can cause or worsen diabetes. If you have symptoms of high blood sugar, please tell your doctor immediately. For example, your doctor may need to adjust your diabetes medication, exercise plan, or diet.

Serious Side Effects

If you experience any of these unlikely but serious side effects, please tell your doctor immediately:

       Abnormal tiredness

       Swollen ankles/foot

       Abnormal weight gain

       Blurred vision

       Easy bruising/bleeding

       Facial swelling

       Abnormal hair growth

       Mental Mood swings/changes (depression, mood swings, agitation)

       Muscle weakness/pain

       Thinning of the skin

       Slow wound healing

       Bone pain

       Chest Pain


       Gastric/intestinal bleeding symptoms (such as stomach/stomach pain, black stool/tar, ground-like Vomiting)

Severe Allergic Reactions

Very severe allergic reactions to this drug are rare. However, if you experience symptoms of a severe allergic reaction such as skin rash, seek medical help immediately. Itching/swelling (especially face/tongue/throat), severe dizziness, shortness of breath.

Does Prednisolone interact with other drugs you are taking?

Drug interactions can change the way drugs work or increase the risk of serious side effects. Keep a list of all products you use and tell your doctor and pharmacist. Do not start, stop or change the dosage of any medicine without the approval of your doctor.

Some products that may interact with this drug are aldesleukin, other drugs that weaken the immune system, such as azathioprine, cyclosporine, cancer chemotherapy, and mifepristone, which may cause bleeding/bruising. Drugs (including antiplatelet drugs such as clopidogrel, "blood thinners" such as dabigatran/warfarin, and non-steroidal anti-inflammatory drugs such as aspirin/celecoxib/ibuprofen) interact with it.

Other products such as estrogen, azole antifungal drugs, rifamycin, St. John's wort, can affect the removal of prednisolone from the body will affect the effects of prednisolone. For more information, please consult your doctor or pharmacist.

This product will affect certain laboratory tests (such as skin tests). Make sure that the laboratory staff and all your doctors know that you are taking this medication.

Have you ever had to take  Prednisolone? 

How did it effect you?

Please comment below

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Lee-Anne x 

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